Further definition by cytotoxicity tests of cell surface antigens of human sarcomas in culture.
نویسنده
چکیده
Antibodies against cell surface antigens of human sarcomas were detected by a complement-dependent cytotoxicity test. Exogenous rabbit complement was required. Sera were titrated in doubling dilutions to a 50% survival end point, relative to control sera. Test cells were obtained from 21 cell cultures derived from sarcoma specimens, and 9 cultures of non-sarcoma cells. Two lines of evidence indicated that sarcoma-related antigens were detected: (a) sarcoma patients' sera were cytotoxic to the patients' own sarcoma cells in
منابع مشابه
Further Definition by Cytotoxicity Tests of Cell Surface Antigens of Human Sarcomas in Culture1
Antibodies against cell surface antigens of human sarcomas were detected by a complement-dependent cytotoxicity test. Exogenous rabbit complement was required. Sera were titrated in doubling dilutions to a 50% survival end point, relative to control sera. Test cells were obtained from 21 cell cultures derived from sarcoma specimens, and 9 cultures of non-sarcoma cells. Two lines of evidence ind...
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عنوان ژورنال:
- Cancer research
دوره 32 5 شماره
صفحات -
تاریخ انتشار 1972